Hormonal Investigations

AMH(Anti- Mullerian Hormone): The Anti-Mullerian Hormone is a hormone produced by granulosa cells of growing follicles (during early stages of their development) in the ovaries. This hormone determines ovarian reserve in other words it defines the quantity but not the quality of follicles in the ovaries. In healthy women the Anti-Mullerian Hormone levels initially increase until early adulthood, and then slowly decrease with increasing age until becoming undetectable.

FSH(Follicle Stimulating Hormone), LH(Luteinizing Hormone): These hormones are produced by the anterior pituitary gland and they regulate the development and growth of the body. They govern pubertal maturation and reproductive processes of the body. In young women, an acute rise in FSH and LH in blood triggers the process of ovulation.The levels of the Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) are usually measured to determine the exact cause of infertility.

Thyroid Profile: The TSH test measures the level of Thyroid-Stimulating Hormone in your blood. The TSH has a normal test range between 0.4 and 4.0 milli-international units of hormone per liter of blood (mIU/L). The effect is felt in the entire endocrine system leading to female hormonal imbalance, menstrual cycle irregularity and infertility.

Prolactin, Estradiol & Progesterone: The most important role of Prolactin is to stimulate milk production in women after the delivery of a baby. High Prolactin may cause infertility in several different ways. First, prolactin may stop a woman from ovulating. If this occurs, a woman’s menstrual cycles will stop. In less severe cases, high prolactin levels may only disrupt ovulation once in a while. This would result in intermittent ovulation or ovulation that takes a long time to occur, Women in this category may experience infrequent or irregular periods.

The estradiol test is a very common diagnostic procedure used to help evaluate your ovarian reserve.

Checking progesterone levels is a reliable way to determine whether a woman has ovulated.There is little medical data to support the notion that “low” progesterone levels are associated with infertility or miscarriage.

CA125, ßHCG & afetoprotein(AFP): This test measures the amount of the protein CA 125 (cancer antigen 125) in your blood. In some cases, a CA 125 test may be used to look for early signs of ovarian cancer in people with a very high risk of the disease. A CA 125 test isn’t accurate enough to use for ovarian cancer screening in general because many noncancerous conditions can increase the CA 125 level. Many different conditions can cause an increase in CA 125, including normal conditions, such as menstruation, and noncancerous conditions, such as uterine fibroids. Certain cancers may also cause an increased level of CA 125, including ovarian, endometrial, peritoneal and fallopian tube cancers.

HCG (Human Chorionic Gonadotropin) is often called the pregnancy hormone because it is made by cells formed in the placenta, which nourishes the egg after it has been fertilized and becomes attached to the uterine wall. Typically, the hCG levels will double every 72 hours. The level will reach its peak in the first 8-11 weeks of pregnancy and then will decline and level off for the remainder of the pregnancy.

The AFP test is especially important for women who are at high risk of having children with birth defects, including women: who are 35 or older, with a family history of birth defects, who used harmful medications or drugs during their pregnancies ,who have diabetes

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