Physiological intracytoplasmic sperm injection (PICSI) is a technique used to select sperm to use in Intracytoplasmic sperm injection (ICSI) treatment. It involves placing sperm with hyaluronic acid (HA), a natural compound found in the body.
The procedure of PICSI is extremely beneficial for males whose sperms have high degree of DNA fragmentation. PICSI chooses the most genetically healthy sperm which increases the chances of fertilization.
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