Laser-Assisted Hatching (LAH) is an in vitro fertilization (IVF) technique that uses a laser to create a small opening in an embryo’s outer layer, known as the Zona Pellucida, to help it hatch. The procedure is typically performed on the third day of embryo development, but can also be used on embryos that have been frozen and thawed.
LAH may be beneficial for embryos whose Zona Pellucida layer is abnormally thick or stiff, as this could prevent the embryo from hatching. Difficulty in hatching is linked to a reduced chance of the embryo attaching to the uterine wall and implanting, both of which are necessary for pregnancy to occur.
LAH involves directing a few concentrated laser pulses at the embryo’s outer shell from a distance, minimizing the risk of damage to the embryo’s cells. The procedure usually takes only a few seconds per embryo and can be performed by an experienced embryologist.
