Laser-assisted hatching (LAH) is an in vitro fertilization (IVF) technique that uses a laser to create a small opening in an embryo’s outer layer, or Zona Pellucida, to help it hatch. Thе procеdurе is typically pеrformеd on thе third day of embryo dеvеlopmеnt, but can also bе usеd on еmbryos that have been frozen and thawed.
Treatment with LAH may be beneficial for embryos whose Zona Pellucida layers are abnormally thick or stiff, as this could prevent the embryo from hatching. Hatching difficulty is positively connected with an embryo’s chances of sticking to the uterine wall and implanting, both of which are necessary for pregnancy to occur.
LAH involves shooting a few concentrated laser pulses at the embryo’s outer shell, from a distance to reduce the risk of damaging the embryo’s cells. The procedure usually takes only a few seconds per embryo, and can be performed by an experienced embryologist.